EMERGING TECHNOLOGIES: DATA SYSTEMS AND DEVICES| JANUARY 04 2023
Simplified Meal Announcement Versus Precise Carbohydrate Counting in Adolescents With Type 1 Diabetes Using the MiniMed 780G Advanced Hybrid Closed Loop System: A Randomized Controlled Trial Comparing Glucose Control
EMERGING TECHNOLOGIES: DATA SYSTEMS AND DEVICES| JANUARY 04 2023
Simplified Meal Announcement Versus Precise Carbohydrate Counting in Adolescents With Type 1 Diabetes Using the MiniMed 780G Advanced Hybrid Closed Loop System: A Randomized Controlled Trial Comparing Glucose Control
Goran Petrovski ; Judith Campbell; Maheen Pasha; Emma Day; Khalid Hussain; Amel Khalifa;
EMERGING TECHNOLOGIES: DATA SYSTEMS AND DEVICES| JANUARY 04 2023
Simplified Meal Announcement Versus Precise Carbohydrate Counting in Adolescents With Type 1 Diabetes Using the MiniMed 780G Advanced Hybrid Closed Loop System: A Randomized Controlled Trial Comparing Glucose Control
Corresponding author: Goran Petrovski, gpetrovski@sidra.org
Diabetes Care dc221692
OBJECTIVE
We aimed to compare glucose control in adolescents with type 1 diabetes (T1D) using the MiniMed 780G system who used simplified meal announcement with those who used precise carbohydrate counting.
RESEARCH DESIGN AND METHODS
This randomized controlled trial included 34 participants (age 12–18 years) with T1D who were on multiple daily injections or insulin pump and were scheduled to start using the MiniMed 780G system at Sidra Medicine in Qatar. After a 7-day run-in period, participants were randomly assigned to the fix group (simplified meal announcement by preset of three personalized fixed carbohydrate amounts) or the flex group (precise carbohydrate counting) and followed for 12 weeks. Between-group difference in time in range (TIR) was the primary end point. Secondary end points included HbA1c and other glycometrics.
RESULTS
During the 12-week study phase, TIR was 73.5 ± 6.7% in the fix and 80.3 ± 7.4% in the flex group, with a between-group difference of 6.8% in favor of flex (P = 0.043). Time >250 mg/dL was better in the flex group (P = 0.012), whereas HbA1c (P = 0.168), time below range (P = 0.283), and time between 180 and 250 mg/dL (P = 0.114) did not differ.
CONCLUSIONS
Adolescents using the MiniMed 780G system with a preset of three personalized fixed carbohydrate amounts can reach international targets of glycemic control. Therefore, it may be a valuable alternative to precise carbohydrate counting in users who are challenged by precise carbohydrate counting. Because carbohydrate counting further improves outcomes, these skills remain important for MiniMed 780G users.
Graphical Abstract
Clinical trial reg. no. NCT05069727; clinicaltrials.gov
This article contains supplementary material online at https://doi.org/10.2337/figshare.21685190.
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Simplified Meal Announcement versus Precise Carbohydrate Counting in Adolescents with Type 1 Diabetes using the MiniMed 780G Advanced Hybrid Closed Loop System: A Randomized Controlled Trial Comparing Glucose Control
Извор https://diabetesjournals.org/care/article-abstract/doi/10.2337/dc22-1692/148250/Simplified-Meal-Announcement-Versus-Precise?mibextid=Zxz2cZ&fbclid=IwAR1fcPX-4du7zKPYYFxpPW8JxN8CPfQMx_eyKglsCe5u334IPISWpTRUy_Y
